Neuronal apoptosis by HIV-1 Vpr: contribution of proinflammatory molecular networks from infected target cells

Neuronal apoptosis by HIV-1 Vpr: contribution of proinflammatory molecular networks from infected target cells

<p>Abstract</p> <p>Background</p> <p>Human immunodeficiency virus type 1 (HIV-1) induces neuronal dysfunction through host cellular factors and viral proteins including viral protein R (Vpr) released from infected macrophages/microglia. Vpr is important for infection of...

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Bibliographic Details
Main Authors: Guha Debjani, Nagilla Pruthvi, Redinger Carrie, Srinivasan Alagarsamy, Schatten Gerald P, Ayyavoo Velpandi
Format: Article
Language:English
Published: BMC 2012-06-01
Series:Journal of Neuroinflammation
Subjects:
HIV-1Vpr
Macrophages
Neuropathogenesis
Proinflammatory cytokines
Online Access:http://www.jneuroinflammation.com/content/9/1/138

Internet

http://www.jneuroinflammation.com/content/9/1/138

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