MicroRNA miR-491-5p Targeting both TP53 and Bcl-XL Induces Cell Apoptosis in SW1990 Pancreatic Cancer Cells through Mitochondria Mediated Pathway

MicroRNA (miRNA) actively participates in a broad range of cellular processes such as proliferation, differentiation, cell survival and apoptosis. Deregulated expression of miRNA may affect cell growth and eventually lead to cancer. In this study, we found that hsa-miR491-5p (miR491-5p) displays a s...

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Bibliographic Details
Main Authors: Li Liu, Sheng-Qi Hou, Wei-Ye Shi, Bin Liu, Yi Wang, Rong Guo
Format: Article
Language:English
Published: MDPI AG 2012-12-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/17/12/14733