Joint analyses of multi-tissue Hi-C and eQTL data demonstrate close spatial proximity between eQTLs and their target genes

Abstract Background Gene regulation is important for cells and tissues to function. It has been studied from two aspects at the genomic level, the identification of expression quantitative trait loci (eQTLs) and identification of long-range chromatin interactions. It is important to understand their...

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Bibliographic Details
Main Authors: Jingting Yu, Ming Hu, Chun Li
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Genetics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12863-019-0744-x