Procyanidin B2 Activates PPARγ to Induce M2 Polarization in Mouse Macrophages

Procyanidin B2 Activates PPARγ to Induce M2 Polarization in Mouse Macrophages

Procyanidins, a subclass of flavonoids found in commonly consumed foods, possess potential anti-inflammatory activity. Manipulation of M1/M2 macrophage homeostasis is an effective strategy for the treatment of metabolic inflammatory diseases. The objective of this study was to determine the effect o...

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Bibliographic Details
Main Authors: Ying Tian, Chunmiao Yang, Qinyu Yao, Lei Qian, Jia Liu, Xinya Xie, Wen Ma, Xin Nie, Baochang Lai, Lei Xiao, Nanping Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
procyanidin B2
macrophages
macrophage polarization
peroxisome proliferator-activated receptor γ
gene regulation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01895/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.01895/full

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