Chemical Synergy between Ionophore PBT2 and Zinc Reverses Antibiotic Resistance

Chemical Synergy between Ionophore PBT2 and Zinc Reverses Antibiotic Resistance

The rise of bacterial antibiotic resistance coupled with a reduction in new antibiotic development has placed significant burdens on global health care. Resistant bacterial pathogens such as methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus are leading causes of commu...

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Bibliographic Details
Main Authors: Lisa Bohlmann, David M. P. De Oliveira, Ibrahim M. El-Deeb, Erin B. Brazel, Nichaela Harbison-Price, Cheryl-lynn Y. Ong, Tania Rivera-Hernandez, Scott A. Ferguson, Amanda J. Cork, Minh-Duy Phan, Amelia T. Soderholm, Mark R. Davies, Graeme R. Nimmo, Gordon Dougan, Mark A. Schembri, Gregory M. Cook, Alastair G. McEwan, Mark von Itzstein, Christopher A. McDevitt, Mark J. Walker
Format: Article
Language:English
Published: American Society for Microbiology 2018-12-01
Series:mBio
Subjects:
Enterococcus faecium
Staphylococcus aureus
Streptococcus pyogenes
antibiotic resistance
Online Access:https://doi.org/10.1128/mBio.02391-18

Internet

https://doi.org/10.1128/mBio.02391-18

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