Inclusion Complex of Docetaxel with Sulfobutyl Ether β-Cyclodextrin: Preparation, In Vitro Cytotoxicity and In Vivo Safety

Docetaxel (DTX), as a first-line anti-tumor drug, has been studied for decades for its diverse bioactivities. However, DTX presents poor solubility in water, low bioavailability and serious toxic side effects which has hindered its application in the clinic. To address these problems, docetaxel-sulf...

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Bibliographic Details
Main Authors: Lili Ren, Xiaolong Yang, Weilu Guo, Jin Wang, Guoguang Chen
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/12/10/2336