Necrostatin-1 Attenuates Inflammatory Response and Improves Cognitive Function in Chronic Ischemic Stroke Mice

Necrostatin-1 Attenuates Inflammatory Response and Improves Cognitive Function in Chronic Ischemic Stroke Mice

Multiple cell death is involved in ischemic brain injury. Necroptosis, a recently reported cell death, may be the most suitable cell death mechanism in a subpopulation of neurons under ischemic injury. It reported that a small molecule, necrostatin-1 (Nec-1), has a potent inhibitory effect on necrop...

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Bibliographic Details
Main Authors: Shehong Zhang, Yuyang Wang, Dake Li, Junfa Wu, Wen Si, Yi Wu
Format: Article
Language:English
Published: MDPI AG 2016-07-01
Series:Medicines
Subjects:
necroptosis
ischemia
cognition
inflammation
Online Access:http://www.mdpi.com/2305-6320/3/3/16

Internet

http://www.mdpi.com/2305-6320/3/3/16

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