Structural and functional studies on the interaction of GspC and GspD in the type II secretion system.

Type II secretion systems (T2SSs) are critical for secretion of many proteins from Gram-negative bacteria. In the T2SS, the outer membrane secretin GspD forms a multimeric pore for translocation of secreted proteins. GspD and the inner membrane protein GspC interact with each other via periplasmic d...

Full description

Bibliographic Details
Main Authors: Konstantin V Korotkov, Tanya L Johnson, Michael G Jobling, Jonathan Pruneda, Els Pardon, Annie Héroux, Stewart Turley, Jan Steyaert, Randall K Holmes, Maria Sandkvist, Wim G J Hol
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3169554?pdf=render