Bacterial delivery of TALEN proteins for human genome editing.

Transcription Activator-Like Effector Nucleases (TALENs) are a novel class of sequence-specific nucleases that have recently gained prominence for its ease of production and high efficiency in genome editing. A TALEN pair recognizes specific DNA sequences and introduce double-strand break in the tar...

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Bibliographic Details
Main Authors: Jingyue Jia, Yongxin Jin, Ting Bian, Donghai Wu, Lijun Yang, Naohiro Terada, Weihui Wu, Shouguang Jin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3950253?pdf=render