Pharmacokinetics of mefloquine administered with artesunate in patients with uncomplicated falciparum malaria from the Brazilian Amazon basin

Abstract Background A fixed-dose combination of mefloquine with artesunate was evaluated in cases of falciparum malaria in the Brazilian Amazon basin with acceptable efficacy, safety and tolerability. However, there are no data on the pharmacokinetics of mefloquine in this coformulation in Brazil, w...

Full description

Bibliographic Details
Main Authors: Michelle V. D. Ferreira, José L. F. Vieira, Eduardo D. Almeida, Juan G. B. Rivera, Margarete S. M. Gomes, André M. de Siqueira
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Malaria Journal
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12936-018-2416-0