The Light Intermediate Chain 2 Subpopulation of Dynein Regulates Mitotic Spindle Orientation

The Light Intermediate Chain 2 Subpopulation of Dynein Regulates Mitotic Spindle Orientation

Abstract Cytoplasmic dynein 1 is a multi-protein intracellular motor essential for mediating several mitotic functions, including the establishment of proper spindle orientation. The functional relevance and mechanistic distinctions between two discrete dynein subpopulations distinguished only by Li...

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Bibliographic Details
Main Authors: Sagar Mahale, Megha Kumar, Amit Sharma, Aswini Babu, Shashi Ranjan, Chetana Sachidanandan, Sivaram V. S. Mylavarapu
Format: Article
Language:English
Published: Nature Publishing Group 2016-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-016-0030-3

Internet

https://doi.org/10.1038/s41598-016-0030-3

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