Dynamic Length Changes of Telomeres and Their Nuclear Organization in Chronic Myeloid Leukemia

Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by the t(9;22) translocation. As in most cancers, short telomeres are one of the features of CML cells, and telomere shortening accentuates as the disease progresses from the chronic phase to the blastic phase. Although mo...

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Bibliographic Details
Main Author: Oumar Samassekou
Format: Article
Language:English
Published: MDPI AG 2013-08-01
Series:Cancers
Subjects:
ALT
Online Access:http://www.mdpi.com/2072-6694/5/3/1086