Dynamic Length Changes of Telomeres and Their Nuclear Organization in Chronic Myeloid Leukemia
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by the t(9;22) translocation. As in most cancers, short telomeres are one of the features of CML cells, and telomere shortening accentuates as the disease progresses from the chronic phase to the blastic phase. Although mo...
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Format: | Article |
Language: | English |
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MDPI AG
2013-08-01
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Series: | Cancers |
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Online Access: | http://www.mdpi.com/2072-6694/5/3/1086 |