Engineered Antigen-Specific T Cells Secreting Broadly Neutralizing Antibodies: Combining Innate and Adaptive Immune Response against HIV

Engineered Antigen-Specific T Cells Secreting Broadly Neutralizing Antibodies: Combining Innate and Adaptive Immune Response against HIV

While antiretroviral therapy (ART) can completely suppress viremia, it is not a cure for HIV. HIV persists as a latent reservoir of infected cells, able to evade host immunity and re-seed infection following cessation of ART. Two promising immunotherapeutic strategies to eliminate both productively...

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Bibliographic Details
Main Authors: Allison B. Powell, Yanqin Ren, Maria Korom, Devin Saunders, Patrick J. Hanley, Harris Goldstein, Douglas F. Nixon, Catherine M. Bollard, Rebecca M. Lynch, R. Brad Jones, Conrad Russell Y. Cruz
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
HIV
antigen-specific T cells
broadly neutralizing antibodies
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050120301819

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http://www.sciencedirect.com/science/article/pii/S2329050120301819

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