Respiratory Manifestations of the Activated Phosphoinositide 3-Kinase Delta Syndrome

Respiratory Manifestations of the Activated Phosphoinositide 3-Kinase Delta Syndrome

The activated phosphoinositide 3-kinase δ syndrome (APDS), also known as p110δ-activating mutation causing senescent T cells, lymphadenopathy, and immunodeficiency (PASLI), is a combined immunodeficiency syndrome caused by gain-of-function mutations in the phosphoinositide 3-kinase (PI3K) genes PIK3...

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Bibliographic Details
Main Authors: Alison M. Condliffe, Anita Chandra
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Immunology
Subjects:
activated phosphoinositide 3-kinase delta syndrome
respiratory infection
pneumonia
bronchiectasis
antibody deficiency
lymphoproliferation
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00338/full

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http://journal.frontiersin.org/article/10.3389/fimmu.2018.00338/full

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