Comparative proteomic analysis of the PhoP regulon in Salmonella enterica serovar Typhi versus Typhimurium.

BACKGROUND:S. Typhi, a human-restricted Salmonella enterica serovar, causes a systemic intracellular infection in humans (typhoid fever). In comparison, S. Typhimurium causes gastroenteritis in humans, but causes a systemic typhoidal illness in mice. The PhoP regulon is a well studied two component...

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Main Authors: Richelle C Charles, Jason B Harris, Michael R Chase, Lauren M Lebrun, Alaullah Sheikh, Regina C LaRocque, Tanya Logvinenko, Sean M Rollins, Abdullah Tarique, Elizabeth L Hohmann, Ian Rosenberg, Bryan Krastins, David A Sarracino, Firdausi Qadri, Stephen B Calderwood, Edward T Ryan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2736619?pdf=render