Association between TCF7L2 Genotype and Glycemic Control in Diabetic Patients Treated with Gliclazide

Previous studies showed associations between variants in TCF7L2 gene and the therapeutic response to sulfonylureas. All sulfonylureas stimulate insulin secretion by the closure of ATP-sensitive potassium (KATP) channel. The aim of the present study was to compare TCF7L2 genotype specific effect of g...

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Bibliographic Details
Main Authors: Martin Javorský, Eva Babjaková, Lucia Klimčáková, Zbynek Schroner, Jozef Židzik, Mária Štolfová, Ján Šalagovič, Ivan Tkáč
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2013/374858