Resistance of melanized yeast cells of Paracoccidioides brasiliensis to antimicrobial oxidants and inhibition of phagocytosis using carbohydrates and monoclonal antibody to CD18

Resistance of melanized yeast cells of Paracoccidioides brasiliensis to antimicrobial oxidants and inhibition of phagocytosis using carbohydrates and monoclonal antibody to CD18

Paracoccidioides brasiliensis, a thermal dimorphic fungal pathogen, produces a melanin-like pigment in vitro and in vivo. We investigated the involvement of carbohydrates and monoclonal antibody to CD18, on phagocytosis inhibition, involving macrophage receptors and the resistance of melanized funga...

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Bibliographic Details
Main Authors: Marcelo Barbosa da Silva, Luciana Thomaz, Alexandre Ferreira Marques, Artur E Svidzinski, Josh D Nosanchuk, Arturo Casadevall, Luiz R Travassos, Carlos P Taborda
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2009-07-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
melanin
P. brasiliensis
antimicrobial oxidants
anti-CD18 antibody
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762009000400019

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762009000400019

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