Diagnostic value of cerebrospinal fluid tau, neurofilament, and progranulin in definite frontotemporal lobar degeneration

Diagnostic value of cerebrospinal fluid tau, neurofilament, and progranulin in definite frontotemporal lobar degeneration

Abstract Background We explored the diagnostic performance of cerebrospinal fluid (CSF) biomarkers in allowing differentiation between frontotemporal lobar degeneration (FTLD) and Alzheimer’s disease (AD), as well as between FTLD pathological subtypes. Methods CSF levels of routine AD biomarkers (ph...

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Bibliographic Details
Main Authors: Joery Goossens, Maria Bjerke, Sara Van Mossevelde, Tobi Van den Bossche, Johan Goeman, Bart De Vil, Anne Sieben, Jean-Jacques Martin, Patrick Cras, Peter Paul De Deyn, Christine Van Broeckhoven, Julie van der Zee, Sebastiaan Engelborghs
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Alzheimer’s Research & Therapy
Subjects:
Frontotemporal lobar degeneration
Alzheimer’s disease
Cerebrospinal fluid
Biomarkers
Differential diagnosis
Tau
Online Access:http://link.springer.com/article/10.1186/s13195-018-0364-0

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http://link.springer.com/article/10.1186/s13195-018-0364-0

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