Chemotherapy and radiation regimens to breast cancer treatment induce changes in mRNA levels of renin–angiotensin system related genes in cardiac tissue

Background and aim: Cardiovascular complications are one limitation of breast cancer treatment. The aim of the current study was to investigate whether the renin–angiotensin related genes could be altered by chemotherapy and radiotherapy, using a rat model. Methods: Female rats were divided into thr...

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Bibliographic Details
Main Authors: Camila Salata, Samara Cristina Ferreira-Machado, André Luiz Mencalha, Cherley Borba Vieira de Andrade, Vera Maria Araújo de Campos, Carlos Alberto Mandarim-de-Lacerda, Carlos Eduardo deAlmeida
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2013-12-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320312465218