Selective impact of HIV disease progression on the innate immune system in the human female reproductive tract.

We have previously demonstrated intrinsic anti-HIV activity in cervicovaginal lavage (CVL) from HIV-infected women with high CD4 counts and not on antiretroviral therapy. However, the impact of HIV disease progression on CVL innate immune responses has not been delineated.CVL from 57 HIV-infected wo...

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Bibliographic Details
Main Authors: Timothy Lahey, Mimi Ghosh, John V Fahey, Zheng Shen, Lucy R Mukura, Yan Song, Susan Cu-Uvin, Kenneth H Mayer, Peter F Wright, John C Kappes, Christina Ochsenbauer, Charles R Wira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3366961?pdf=render