Distinct effects of IL-18 on the engraftment and function of human effector CD8 T cells and regulatory T cells.
IL-18 has pleotropic effects on the activation of T cells during antigen presentation. We investigated the effects of human IL-18 on the engraftment and function of human T cell subsets in xenograft mouse models. IL-18 enhanced the engraftment of human CD8(+) effector T cells and promoted the develo...
Main Authors: | , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-09-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2538560?pdf=render |