Effect of bile pigments on the compromised gut barrier function in a rat model of bile duct ligation.

BACKGROUND: Studies have shown that the absence of bile in the gut lumen, either by bile duct ligation or bile diversion, induces mucosal injury. However, the mechanism remains elusive. In this study, the role of bile pigments in gut barrier function was investigated in a rat model of bile duct liga...

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Bibliographic Details
Main Authors: Kangkang Zhou, Mingshan Jiang, Yuanli Liu, Yilin Qu, Guojing Shi, Xinguang Yang, Xiaofa Qin, Xiuhong Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4044053?pdf=render