A positive feedback mechanism that regulates expression of miR-9 during neurogenesis.

MiR-9, a neuron-specific miRNA, is an important regulator of neurogenesis. In this study we identify how miR-9 is regulated during early differentiation from a neural stem-like cell. We utilized two immortalized rat precursor clones, one committed to neurogenesis (L2.2) and another capable of produc...

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Bibliographic Details
Main Authors: Jonathan L Davila, Loyal A Goff, Christopher L Ricupero, Cynthia Camarillo, Eileen N Oni, Mavis R Swerdel, Alana J Toro-Ramos, Jiali Li, Ronald P Hart
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3979806?pdf=render