Fibronectin matrix assembly suppresses dispersal of glioblastoma cells.

Glioblastoma (GBM), the most aggressive and most common form of primary brain tumor, has a median survival of 12-15 months. Surgical excision, radiation and chemotherapy are rarely curative since tumor cells broadly disperse within the brain. Preventing dispersal could be of therapeutic benefit. Pre...

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Bibliographic Details
Main Authors: Joshua Sabari, Daniel Lax, Daniel Connors, Ian Brotman, Eric Mindrebo, Christine Butler, Ildiko Entersz, Dongxuan Jia, Ramsey A Foty
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3184095?pdf=render