C282Y-HFE gene variant affects cholesterol metabolism in human neuroblastoma cells.

Although disruptions in the maintenance of iron and cholesterol metabolism have been implicated in several cancers, the association between variants in the HFE gene that is associated with cellular iron uptake and cholesterol metabolism has not been studied. The C282Y-HFE variant is a risk factor fo...

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Bibliographic Details
Main Authors: Fatima Ali-Rahmani, Michael A Huang, C-L Schengrund, James R Connor, Sang Y Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3922969?pdf=render