Hypoxia Promotes Prostate Cancer Aggressiveness by Upregulating EMT-Activator Zeb1 and SK3 Channel Expression

Hypoxia Promotes Prostate Cancer Aggressiveness by Upregulating EMT-Activator Zeb1 and SK3 Channel Expression

Hypoxia is a well-established feature of prostate cancer (PCa) and is associated with disease aggressiveness. The hypoxic microenvironment initiates multiple adaptive responses including epithelial-to-mesenchymal transition (EMT) and a remodeling of calcium homeostasis involved in cancer progression...

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Bibliographic Details
Main Authors: Fanny Bery, Sandy Figiel, Sana Kouba, Delphine Fontaine, Maxime Guéguinou, Marie Potier-Cartereau, Christophe Vandier, Roseline Guibon, Franck Bruyère, Gaëlle Fromont, Karine Mahéo
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
prostate cancer
hypoxia
Zeb1
calcium
lipids
Online Access:https://www.mdpi.com/1422-0067/21/13/4786

Internet

https://www.mdpi.com/1422-0067/21/13/4786

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