In silico and antithrombotic studies of 1,3,4-oxadiazoles derived from benzimidazole
In the present study, a series of 1,3,4-oxadiazole derivatives (4a-4k) derived from benzimidazole were docked onto factor Xa (PDB: 1NFY) protein using SYBYLX 2.1. and also evaluated for in vitro clot lysis for thrombolytic activity. The synthesized molecules were also screened for in silico ADME stu...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Bangladesh Pharmacological Society
2015-12-01
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| Series: | Bangladesh Journal of Pharmacology |
| Subjects: | |
| Online Access: | https://www.banglajol.info/index.php/BJP/article/view/23981 |