Exosomes are unlikely involved in intercellular Nef transfer.

HIV-1 Nef is an important pathogenic factor for HIV/AIDS pathogenesis. Several recent studies including ours have demonstrated that Nef can be transferred to neighboring cells and alters the function of these cells. However, how the intercellular Nef transfer occurs is in dispute. In the current stu...

Full description

Bibliographic Details
Main Authors: Xiaoyu Luo, Yan Fan, In-Woo Park, Johnny J He
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4412529?pdf=render