One-pot three component synthesis of substituted dihydropyrimidinones using fruit juices as biocatalyst and their biological studies.

New and facile one-pot three component approach for the synthesis of substituted dihydropyrimidinones derivatives (4a-4h) from reaction of equimolar substituted aldehydes (1a-1h), methyl acetoacetate (2a) and urea (3a) in presence of nature derived catalyst viz. Cocos nucifera L. juice, Solanum lyco...

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Bibliographic Details
Main Authors: Susheel Gulati, Rajvir Singh, Ram Prakash, Suman Sangwan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0238092