Dissecting the role of PfAP2-G in malaria gametocytogenesis

The transcription factor PfAP2-G is a key determinant of sexual commitment in Plasmodium falciparum. Here, Josling et al. define the transcriptional regulatory network of PfAP2-G by identifying its DNA binding sites genome-wide, which vary depending on the route of sexual conversion and rely on inte...

Full description

Bibliographic Details
Main Authors: Gabrielle A. Josling, Timothy J. Russell, Jarrett Venezia, Lindsey Orchard, Riëtte van Biljon, Heather J. Painter, Manuel Llinás
Format: Article
Language:English
Published: Nature Publishing Group 2020-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15026-0