A new, robust, and nonradioactive approach for exploring N-myristoylation

A new, robust, and nonradioactive approach for exploring N-myristoylation

Myristoyl-CoA (CoA):protein N-myristoyltransferase (NMT) catalyzes protein modification through covalent attachment of a C14 fatty acid (myristic acid) to the N-terminal glycine of proteins, thus promoting protein-protein and protein-membrane interactions. NMT is essential for the viability of numer...

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Bibliographic Details
Main Authors: Francesca Rampoldi, Roger Sandhoff, Robert W. Owen, Hermann-Josef Gröne, Stefan Porubsky
Format: Article
Language:English
Published: Elsevier 2012-11-01
Series:Journal of Lipid Research
Subjects:
azido-fatty acid
N-myristoyl transferase
protein acylation
Staudinger ligation
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520412635

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520412635

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