Phosphate Derivatives of 3-Carboxyacylbetulin: SynThesis, In Vitro Anti-HIV and Molecular Docking Study

Lupane-type pentacyclic triterpenes such as betulin and betulinic acid play an important role in the search for new therapies that would be effective in controlling viral infections. The aim of this study was the synthesis and evaluation of in vitro anti-HIV-1 activity for phosphate derivatives of 3...

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Bibliographic Details
Main Authors: Krzysztof Marciniec, Elwira Chrobak, Aleksandra Dąbrowska, Ewa Bębenek, Monika Kadela-Tomanek, Paweł Pęcak, Stanisław Boryczka
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/10/8/1148