Continuous warfarin administration versus heparin bridging therapy in post colorectal polypectomy haemorrhage: a study protocol for a multicentre randomised controlled trial (WHICH study)

Continuous warfarin administration versus heparin bridging therapy in post colorectal polypectomy haemorrhage: a study protocol for a multicentre randomised controlled trial (WHICH study)

Abstract Background Endoscopic removal of colorectal adenoma is considered an effective treatment for reducing the mortality rates associated with colorectal cancer. Warfarin, a type of anticoagulant, is widely used for the treatment and prevention of thromboembolism; however, bleeding may increase...

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Main Authors: Yasuaki Nagami, Taishi Sakai, Masafumi Yamamura, Masami Nakatani, Takayuki Katsuno, Takehisa Suekane, Hironori Uno, Hiroaki Minamino, Masatsugu Okuyama, Junichi Okamoto, Mitsutaka Kumamoto, Atsushi Noguchi, Kazuki Yamamori, Osamu Takaishi, Masahiro Ochi, Takako Miyazaki, Shigetsugu Tsuji, Hisatomo Ikehara, Koichiro Kawaguchi, Tomoyuki Hayashi, Tomohiko Mannami, Kazuki Kakimoto, Yoshihide Naito, Satoru Hashimoto, Zhaoliang Li, Yoriaki Komeda, Takaaki Kishino, Yoshinobu Yamamoto, Mikitaka Iguchi, Takuji Akamatsu, Toshiki Horii, Ko Miura, Takeshi Yamashina, Yuusaku Sugihara, Noboru Watanabe, Shu Kiyotoki, Ryoji Fujii, Masaki Murata, Satoshi Ono, Toshiaki Narasaka, Shinji Kitamura, Mitsuhiro Kono, Motohiko Kato, Hideto Kawaratani, Kyosuke Tanaka, Takao Yaoita, Shinjiro Yamaguchi, Keiichiro Abe, Takuji Kawamura, Yosuke Kinoshita, Kenichiro Imai, Haruka Fujinami, Tomoyuki Yada, Hayato Miyamoto, Hisako Yoshida, Yasuhiro Fujiwara
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Trials
Subjects:
Colorectal polypectomy
Anticoagulants
Warfarin
Heparin bridge
Vitamin K antagonist
Online Access:https://doi.org/10.1186/s13063-020-04975-y

Internet

https://doi.org/10.1186/s13063-020-04975-y

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