Synergy between hemagglutinin 2 (HA2) subunit of influenza fusogenic membrane glycoprotein and oncolytic Newcastle disease virus suppressed tumor growth and further enhanced by Immune checkpoint PD-1 blockade

Synergy between hemagglutinin 2 (HA2) subunit of influenza fusogenic membrane glycoprotein and oncolytic Newcastle disease virus suppressed tumor growth and further enhanced by Immune checkpoint PD-1 blockade

Abstract Background Newcastle disease virus (NDV) has shown noticeable oncolytic properties, especially against cervical cancer. However, in order to improve the spread rate and oncotoxicity of the virus, employment of other therapeutic reagents would be helpful. It has been shown that some viral fu...

Full description

Bibliographic Details
Main Authors: Seyed Mohammad Miri, Mir Saeed Ebrahimzadeh, Elahe Abdolalipour, Mahsa Yazdi, Hassan Hosseini Ravandi, Amir Ghaemi
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Cancer Cell International
Subjects:
Cervical cancer
Fusogenic membrane glycoprotein
Newcastle disease virus
PD-1 blockade
Influenza hemagglutinin 2
Online Access:http://link.springer.com/article/10.1186/s12935-020-01476-5

Internet

http://link.springer.com/article/10.1186/s12935-020-01476-5

Similar Items