Functional states of the genome-scale Escherichia coli transcriptional regulatory system.

A transcriptional regulatory network (TRN) constitutes the collection of regulatory rules that link environmental cues to the transcription state of a cell's genome. We recently proposed a matrix formalism that quantitatively represents a system of such rules (a transcriptional regulatory syste...

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Bibliographic Details
Main Authors: Erwin P Gianchandani, Andrew R Joyce, Bernhard Ø Palsson, Jason A Papin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2685017?pdf=render