Image- and Fluorescence-Based Test Shows Oxidant-Dependent Damages in Red Blood Cells and Enables Screening of Potential Protective Molecules

Image- and Fluorescence-Based Test Shows Oxidant-Dependent Damages in Red Blood Cells and Enables Screening of Potential Protective Molecules

An increase of oxygen saturation within blood bags and metabolic dysregulation occur during storage of red blood cells (RBCs). It leads to the gradual exhaustion of RBC antioxidant protective system and, consequently, to a deleterious state of oxidative stress that plays a major role in the appariti...

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Bibliographic Details
Main Authors: Manon Bardyn, Jérôme Allard, David Crettaz, Benjamin Rappaz, Gerardo Turcatti, Jean-Daniel Tissot, Michel Prudent
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
red blood cell
transfusion
antioxidant
oxidant
high-throughput screening
digital holographic microscopy
Online Access:https://www.mdpi.com/1422-0067/22/8/4293

Internet

https://www.mdpi.com/1422-0067/22/8/4293

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