Successful total en bloc spondylectomy of the L3 vertebra with a paravertebral giant cell tumor following preoperative treatment with denosumab: a case report

Successful total en bloc spondylectomy of the L3 vertebra with a paravertebral giant cell tumor following preoperative treatment with denosumab: a case report

Abstract Background Giant cell tumor is known to be a benign neoplasm that arises most commonly in the long bones, while cases in the spine are rare. Recently, denosumab, a monoclonal antibody that inhibits receptor activator of nuclear factor-kappa β ligand, has been used to treat patients with gia...

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Bibliographic Details
Main Authors: Hideyuki Kinoshita, Sumihisa Orita, Tsukasa Yonemoto, Takeshi Ishii, Shintaro Iwata, Hiroto Kamoda, Toshinori Tsukanishi, Kazuhide Inage, Koki Abe, Masahiro Inoue, Masaki Norimoto, Tomotaka Umimura, Kazuki Fujimoto, Yasuhiro Shiga, Hirohito Kanamoto, Takeo Furuya, Kazuhisa Takahashi, Seiji Ohtori
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Journal of Medical Case Reports
Subjects:
Giant cell tumor
Denosumab
Total en bloc spondylectomy
Paravertebral lesion
Online Access:http://link.springer.com/article/10.1186/s13256-019-2029-4

Internet

http://link.springer.com/article/10.1186/s13256-019-2029-4

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