Bone Size and Quality Regulation: Concerted Actions of mTOR in Mesenchymal Stromal Cells and Osteoclasts

Bone Size and Quality Regulation: Concerted Actions of mTOR in Mesenchymal Stromal Cells and Osteoclasts

The bone size and quality, acquired during adolescent growth under the influence of anabolic hormones, growth factors, and nutrients, determine the height and bone stability and forecast osteoporosis risks in late life. Yet bone size and quality control mechanisms remain enigmatic. To study the role...

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Bibliographic Details
Main Authors: Hongguang Wu, Zhixiang Wu, Ping Li, Qian Cong, Rongrong Chen, Wenrui Xu, Soma Biswas, Huijuan Liu, Xuechun Xia, Shanshan Li, Weiwei Hu, Zhenlin Zhang, Samy L. Habib, Lingli Zhang, Jun Zou, Hongbing Zhang, Weihong Zhang, Baojie Li
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Stem Cell Reports
Subjects:
mTOR
mesenchymal stromal cells
MSCs
osteoclast
TSC patient
rapamycin
bone
cartilage
monocyte
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671117301595

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http://www.sciencedirect.com/science/article/pii/S2213671117301595

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