Establishment of long-term serum-free culture for lacrimal gland stem cells aiming at lacrimal gland repair

Abstract Background Aqueous-deficient dry eye disease (ADDED) resulting from dysfunction of the lacrimal gland (LG) is currently incurable. Although LG stem/progenitor cell-based therapy is considered to be a promising strategy for ADDED patients, the lack of a reliable serum-free culture method to...

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Bibliographic Details
Main Authors: Sa Xiao, Yan Zhang
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13287-019-1541-1