7α-Hydroxylation of cholestanol by rat liver microsomes

In a study of the mechanism whereby 5α-bile acids are formed from cholestanol, the 7α-hydroxylation of cholestanol was investigated in rat liver preparations in vitro. It was found that in the presence of NADPH and oxygen, rat liver microsomes catalyzed the 7α-hydroxylation of cholestanol to the sam...

Full description

Bibliographic Details
Main Authors: Sarah Shefer, Susan Hauser, Erwin H. Mosbach
Format: Article
Language:English
Published: Elsevier 1968-05-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520430998