The utility of biomarkers in diagnosis of aspirin exacerbated respiratory disease

Abstract Background Aspirin-exacerbated respiratory disease (AERD) is a distinct eosinophilic phenotype of severe asthma with accompanying chronic rhinosinusitis, nasal polyposis, and hypersensitivity to aspirin. Urinary 3-bromotyrosine (uBrTyr) is a noninvasive marker of eosinophil-catalyzed protei...

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Main Authors: Suzy A. A. Comhair, Grazyna Bochenek, Sara Baicker-McKee, Zeneng Wang, Tomasz Stachura, Marek Sanak, Jeffrey P. Hammel, Stanley L. Hazen, Serpil C. Erzurum, Ewa Nizankowska-Mogilnicka
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Respiratory Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12931-018-0909-6