Ectopic Expression of Genotype 1 Hepatitis E Virus ORF4 Increases Genotype 3 HEV Viral Replication in Cell Culture

Hepatitis E virus (HEV) can account for up to a 30% mortality rate in pregnant women, with highest incidences reported for genotype 1 (gt1) HEV. Reasons contributing to adverse maternal-fetal outcome during pregnancy in HEV-infected pregnant women remain elusive in part due to the lack of a robust t...

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Bibliographic Details
Main Authors: Kush K. Yadav, Patricia A Boley, Zachary Fritts, Scott P Kenney
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/13/1/75