The COL-4A1 polypeptide destroy endothelial cells through the TGF-β/PI3K/AKT pathway

Abstract Preeclampsia (PE) is commonly considered as a placental disorder in pregnancy. Until now, the etiology and pathological mechanism of PE have remained ambiguous. Although PE can lead to a variety of maternal and infant complications, there are still no effective treatments. This study aimed...

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Bibliographic Details
Main Authors: Ting Li, Zhonghui Ling, Kaipeng Xie, Yixiao Wang, Zhijing Miao, Xiaohong Ji, Jingyun Li, Wenwen Hou, Qiuqin Tang, Xiaojie Yuan, Nan Li, Chanjuan Li, Hongjuan Ding
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-94801-5