Curcumin Sensitizes Kidney Cancer Cells to TRAIL-Induced Apoptosis via ROS Mediated Activation of JNK-CHOP Pathway and Upregulation of DR4

Curcumin Sensitizes Kidney Cancer Cells to TRAIL-Induced Apoptosis via ROS Mediated Activation of JNK-CHOP Pathway and Upregulation of DR4

<b> </b>Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL), is a selective anticancer cytokine capable of exerting a targeted therapy approach. Disappointingly, recent research has highlighted the development of TRAIL resistance in cancer cells, thus minimising its usefulne...

Full description

Bibliographic Details
Main Authors: Ismael Obaidi, Hilary Cassidy, Verónica Ibáñez Gaspar, Jasmin McCaul, Michael Higgins, Melinda Halász, Alison L. Reynolds, Breandan N. Kennedy, Tara McMorrow
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Biology
Subjects:
TRAIL
curcumin
chemosensitisation
apoptosis
zebrafish
ROS
Online Access:https://www.mdpi.com/2079-7737/9/5/92

Internet

https://www.mdpi.com/2079-7737/9/5/92

Similar Items