High quality genome-wide genotyping from archived dried blood spots without DNA amplification.

Spots of blood are routinely collected from newborn babies onto filter paper called Guthrie cards and used to screen for metabolic and genetic disorders. The archived dried blood spots are an important and precious resource for genomic research. Whole genome amplification of dried blood spot DNA has...

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Bibliographic Details
Main Authors: Krystal R St Julien, Laura L Jelliffe-Pawlowski, Gary M Shaw, David K Stevenson, Hugh M O'Brodovich, Mark A Krasnow, Stanford BPD Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3667813?pdf=render