T tubules and surface membranes provide equally effective pathways of carbonic anhydrase-facilitated lactic acid transport in skeletal muscle.

T tubules and surface membranes provide equally effective pathways of carbonic anhydrase-facilitated lactic acid transport in skeletal muscle.

We have studied lactic acid transport in the fast mouse extensor digitorum longus muscles (EDL) by intracellular and cell surface pH microelectrodes. The role of membrane-bound carbonic anhydrases (CA) of EDL in lactic acid transport was investigated by measuring lactate flux in muscles from wildtyp...

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Bibliographic Details
Main Authors: Janine Hallerdei, Renate J Scheibe, Seppo Parkkila, Abdul Waheed, William S Sly, Gerolf Gros, Petra Wetzel, Volker Endeward
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3001455?pdf=render

Internet

http://europepmc.org/articles/PMC3001455?pdf=render

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