Membrane-disruptive peptides/peptidomimetics-based therapeutics: Promising systems to combat bacteria and cancer in the drug-resistant era

Membrane-disruptive peptides/peptidomimetics-based therapeutics: Promising systems to combat bacteria and cancer in the drug-resistant era

Membrane-disruptive peptides/peptidomimetics (MDPs) are antimicrobials or anticarcinogens that present a general killing mechanism through the physical disruption of cell membranes, in contrast to conventional chemotherapeutic drugs, which act on precise targets such as DNA or specific enzymes. Owin...

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Bibliographic Details
Main Authors: Liming Lin, Jiaying Chi, Yilang Yan, Rui Luo, Xiaoqian Feng, Yuwei Zheng, Dongyi Xian, Xin Li, Guilan Quan, Daojun Liu, Chuanbin Wu, Chao Lu, Xin Pan
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Membrane-disruptive peptides/peptidomimetics
Drug-resistance
Drug delivery systems
Combination therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S221138352100263X

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http://www.sciencedirect.com/science/article/pii/S221138352100263X

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