𝛽-Thalassemia: HiJAKing Ineffective Erythropoiesis and Iron Overload
𝛽-thalassemia encompasses a group of monogenic diseases that have in common defective synthesis of 𝛽-globin. The defects involved are extremely heterogeneous and give rise to a large phenotypic spectrum, with patients that are almost asymptomatic to cases in which regular blood transfusions are requ...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2010-01-01
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| Series: | Advances in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2010/938640 |