The effect of hypoxia on facial shape variation and disease phenotypes in chicken embryos

SUMMARY Craniofacial anomalies can arise from both genetic and environmental factors, including prenatal hypoxia. Recent clinical evidence correlates hypoxia to craniofacial malformations. However, the mechanisms by which hypoxia mediates these defects are not yet understood. We examined the cellula...

Full description

Bibliographic Details
Main Authors: Francis Smith, Diane Hu, Nathan M. Young, Alexis J. Lainoff, Heather A. Jamniczky, Emin Maltepe, Benedikt Hallgrimsson, Ralph S. Marcucio
Format: Article
Language:English
Published: The Company of Biologists 2013-07-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/6/4/915