Iron regulator hepcidin exhibits antiviral activity against hepatitis C virus.

Hepatitis C viral infection affects 170 million people worldwide. It causes serious chronic liver diseases. HCV infection has been implicated in iron accumulation in the liver and iron overload has been shown to be a potential cofactor for HCV associated hepatocellular carcinoma progression. The und...

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Bibliographic Details
Main Authors: Hongyan Liu, Thu Le Trinh, Huijia Dong, Robertson Keith, David Nelson, Chen Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3478283?pdf=render